Serum Amyloid A for Veterinarian Diagnostic Testing

Accurate Results for Inflammation

VET-SAA ‘Eiken’ is a turbidimetric immunoassay reagent for the measurement of serum amyloid A (SAA) in animal serum and plasma. VET-SAA ‘Eiken’ is designed to be used on general clinical chemistry analyzers.

Why Test For Serum Amyloid A?

SAA Is An Inflammation Marker

SAA is also known as one of the acute phase proteins (APP) in serum and plasma.

Tissue damage, such as trauma, infection, stress, neoplasia and inflammation, triggers acute phase response (APR) as a part of the early-defense or innate immune system.

Testing for SAA will allow for earlier treatment and can be used to monitor treatment and to determine the correct time to end it

Applicable For Multiple Species

The reagent is reactive with the following species: Horse, Cat, Dog, Cattle, Raccoon dog, Shetland pony, Grant’s Zebra, Lion, Cheetah, Blackbuck, Water buffalo, Red Deer, Pig, Bonnet macaque, Crested macaque, Toque macaque, Patas monkey, De Brazza’s guenon, Tufted capuchin, Squirrel monkey, Lar Gibbon, Ring-tailed lemur, Rabbit (In-house data)

Accurate and Cost Effective

The VET-SAA reagent kit is a cost effective testing solution for veterinarian labs running multiple samples per day.

The change of SAA concentrations can provide important prognostic value. For equine SAA, the response time is 6-12 hours and the peak is 48 hours after inflammation starts [*4, 7]. For other species, generally SAA starts increase at 8-12 hours after inflammation occurs, and it reaches maximal levels in 24-48 hours [*8]. As inflammation is resolved, SAA concentration declines in a short term.

“The assay was unique in its ability to measure SAA concentrations with acceptable reliability over an extreme concentration range. This is relevant in the equine species, where SAA concentrations may reach very high concentrations” (Jacobsen et al. 2019)

What's Included?

The Vet-SAA kit contains 4 components:

Vet-SAA Reagent Pack
Calibrator Pack
Low QC Pack
High QC Pack

All components can be purchased together or individually as needed.

Compatible With Multiple Biochemistry Analyzers

The Vet-SAA reagent can be run on industry standard biochemistry analyzer models that support open reagent channels.

Publications and Validations

PubMed: Use of serum amyloid A in equine medicine and surgery. Read Here
BEVA: The acute phase protein serum amyloid A (SAA) as a marker of inflammation in horses. Read Here
PubMed: Validation of an automated immunoturbidimetric assay for feline serum amyloid A. Read Here
PubMed: Canine serum amyloid A (SAA) measured by automated agglutination turbidimetry is useful for routine sensitive and specific detection of systemic inflammation in a general clinical setting. Read Here
PubMed: Sequential changes in hepatic mRNA abundance and serum concentration of serum amyloid A in cattle with acute inflammation caused by endotoxin. Read Here
Read more validations here